Invitrogen™ CALML5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531373

Product Code. 13485887

Description

Recommended positive controls: A431. Predicted reactivity: Human (98%), Rhesus Monkey (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

Specifications

• Antigen: CALML5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALML5
• Gene Alias: call5; Calm4; CALML5; calmodulin 4; calmodulin like 5; calmodulin-like 5; calmodulin-like protein 5; Calmodulin-like skin protein; CLSP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51806
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NZT1
• Gene Symbols: CALML5
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CALML5. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG