Calcium Ionophore A23187 (Free Acid), Fisher BioReagents

Product Code. 10284963

Brand: Fisher BioReagents BP5951

Description

Isolated from Streptomyces chartreusensis

This widely used ionophore increases the permeability of biological membranes for bivalent cations.

Specifications

• CAS: 52665-69-7
• Melting Point: 182°C
• Color: White
• Packaging: Poly Micro Tube
• Molecular Formula: C29H37N3O6
• MDL Number: MFCD00151202,MFCD00151202
• Quantity: 1 mg
• Merck Index: 15, 1642
• Specific Rotation: -50 to -56° (+ or -)
• Synonym: calcimycin, antibiotic a23187, ionophore a23187, calcium ionophore a23187, 4-benzoxazolecarboxylic acid, 5-methylamino-2-3,9,11-trimethyl-8-1-methyl-2-oxo-2-1h-pyrrol-2-yl ethyl-1,7-dioxaspiro 5.5 undec-2-yl methyl-, 6s-6alpha 2s*,3s* ,8beta r* ,9beta,11alpha, spectrum_001976, upcmld-dp093, upcmld-dp093:001, upcmld-dp093:002, upcmld-dp093:003
• InChI Key: HIYAVKIYRIFSCZ-CVXKHCKVSA-N
• SMILES: CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O
• IUPAC Name: 5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
• Molecular Weight (g/mol): 523.63
• PubChem CID: 97043288
• Formula Weight: 523.6
• Percent Purity: 98% min.
• Physical Form: Solid
• Chemical Name or Material: Calcium Ionophore A23187

Safety and Handling

Product Identifier

• Calcium ionophore A23187

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H312-Harmful in contact with skin.
• H332-Harmful if inhaled.
• H302-Harmful if swallowed.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

SDS