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Calcium Ionophore A23187 (Free Acid), Fisher BioReagents

Catalog Number 10284963
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Poly Micro Tube; 1mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Isolated from Streptomyces chartreusensis

This widely used ionophore increases the permeability of biological membranes for bivalent cations.
TRUSTED_SUSTAINABILITY
CAS 52665-69-7
Melting Point 182°C
Color White
Packaging Poly Micro Tube
Molecular Formula C29H37N3O6
MDL Number MFCD00151202,MFCD00151202
Quantity 1 mg
Merck Index 15, 1642
Specific Rotation -50 to -56° (+ or -)
Synonym calcimycin, antibiotic a23187, ionophore a23187, calcium ionophore a23187, 4-benzoxazolecarboxylic acid, 5-methylamino-2-3,9,11-trimethyl-8-1-methyl-2-oxo-2-1h-pyrrol-2-yl ethyl-1,7-dioxaspiro 5.5 undec-2-yl methyl-, 6s-6alpha 2s*,3s* ,8beta r* ,9beta,11alpha, spectrum_001976, upcmld-dp093, upcmld-dp093:001, upcmld-dp093:002, upcmld-dp093:003
InChI Key HIYAVKIYRIFSCZ-CVXKHCKVSA-N
SMILES CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O
IUPAC Name 5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
Molecular Weight (g/mol) 523.63
PubChem CID 97043288
Formula Weight 523.6
Percent Purity 98% min.
Physical Form Solid
Chemical Name or Material Calcium Ionophore A23187
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Product Identifier
  • Calcium ionophore A23187
Signal Word
  • Warning
Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H312-Harmful in contact with skin.
  • H332-Harmful if inhaled.
  • H302-Harmful if swallowed.
Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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