CAD Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA521352

Product Code. 13288958

Description

Recommended positive controls: 293T, C2C12. Predicted reactivity: Mouse (92%), Rat (92%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Specifications

• Antigen: CAD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAD
• Gene Alias: 2410008J01Rik; 38E.19; anon-WO2004063362.83; Aspartate carbamoyltransferase; AU018859; cad; CAD protein; CAD trifunctional protein; cad-PA; cad-PB; cad-PC; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; carbamyl phosphatate synthetase 2; caudal; cb456; cd; CDG1Z; CG1759; CG1759-PA; CG1759-PB; CG1759-PC; Cpad; Dihydroorotase; Dmel\CG1759; Dmel_CG1759; Glutamine-dependent carbamoyl-phosphate synthase; Homeotic protein caudal; LD29596p; multifunctional protein CAD; S67; si:dkey-221h15.3; wu:fc30c12; wu:fc33d01; wu:fc67g02
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 69719, 790
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.41 mg/mL
• Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: B2RQC6, P27708
• Gene Symbols: CAD
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1625 and 1930 of CAD (Uniprot ID#P27708)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG