Invitrogen™ CACNB2 Monoclonal Antibody (N8b/1), PE

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA545453

Product Code. 17877522

Description

1 μg/mL of MA5-45453 was sufficient for detection of Cav beta2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody Detects approximately 78 kDa. No cross reactivity against Cav beta 1, Cav beta 3, Cav beta 4.

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

Specifications

• Antigen: CACNB2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: Q08289, Q8CC27, Q8VGC3
• Gene Symbols: Cacnb2
• Immunogen: Synthetic peptide amino acids 189-205 of rat CavBeta2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Microarray
• Clone: N8b/1
• Conjugate: PE
• Gene: Cacnb2
• Gene Alias: AW060387; brain calcium channel beta-subunit CaB2c (splice variant of the gene CaB2); CAB1; CAB2; Cacnb2; CACNLB1; Cacnlb2; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; calcium voltage-gated channel auxiliary subunit beta 2; cardiac calcium channel beta subunit; cardiac calcium channel beta-subunit CaB2a (splice variant of the gene CaB2; cardiac calcium channel beta-subunit CaB2b (splice variant of the gene CaB2); CAVB2; Cavbeta2; Cchb2; CCHLB1; lambert-Eaton myasthenic syndrome antigen B; L-type calcium channel beta subunit; L-type voltage-dependent calcium channel beta-2 subunit; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; voltage-dependent calcium channel beta2A subunit; voltage-dependent calcium channel beta2B subunit; voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 116600, 12296, 783
• Content And Storage: 4°C
• Form: Liquid