Invitrogen™ CABC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584511

Product Code. 16321465

Description

Immunogen sequence: LGDTIMVAKG LVKLTQAAVE THLQHLGIGG ELIMAARALQ STAVEQIGMF LGKVQGQDKH EEYFAENFGG PEGEFHFSVP HAAG Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 74%.

ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.

Specifications

• Antigen: CABC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COQ8A
• Gene Alias: 4632432J16Rik; aarF domain containing kinase 3; aarF domain-containing protein kinase 3; Adck3; AI462003; ARCA2; atypical kinase ADCK3, mitochondrial; Atypical kinase COQ8A, mitochondrial; Cabc1; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; chaperone, ABC1 activity of bc1 complex like; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog; coenzyme Q8A; COQ10D4; COQ8; COQ8A; mKIAA0451; PP265; SCAR9
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56997
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NI60
• Gene Symbols: COQ8A
• Immunogen: Recombinant protein corresponding to Human COQ8A. Recombinant protein control fragment (Product #RP-107086).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG