Invitrogen™ C8A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568482

Product Code. 15869242

Description

Predicted to react with Human samples.

C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.

Specifications

• Antigen: C8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C8A
• Gene Alias: C8a; complement component 8 alpha subunit; complement component 8 subunit alpha; complement component 8, alpha polypeptide; complement component C8 alpha chain
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 731
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P07357
• Gene Symbols: C8A
• Immunogen: Synthesized peptide derived from human C8A [aa 201-250].
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG