Invitrogen™ C1GALT1C1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5121119

Product Code. 17772514

Description

Positive test controls include: HeLa, Mouse liver, Mouse kidney. The target is usually found in the following locations: Membrane, Single-pass type II membrane protein. Immunogen sequence: IGHGNRMHHH EHHHLQAPNK EDILKISEDE RMELSKSFRV YCIILVKPKD VSLWAAVKET WTKHCDKAEF FSSENVKVFE SINMDTNDMW LMMRKAYKYA FDKYRDQYNW FFLARPTTFA IIENLKYFLL KKDPSQPFYL GHTIKSGDLE YVGMEGGIVL S.

This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Specifications

• Antigen: C1GALT1C1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1GALT1C1
• Gene Alias: 1500002I11Rik; AB030184; beta 1,3-galactosyltransferase 2; beta1,3-galactosyltransferase 2; C1GALT1 specific chaperone 1; C1galt1c1; C1GALT1-specific chaperone 1; C1GALT2; C1Gal-T2; C38H2-L1; C38H2-like protein 1; C81205; core 1 beta1,3-galactosyltransferase 2; core 1 beta3-galactosyltransferase-specific molecular chaperone; core 1 beta3-Gal-T2; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2; COSMC; HSPC067; mC1Gal-T2; MST143; MSTP143; RGD1311230; TNPS; UNQ273/PRO310
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29071, 302499, 59048
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q499P3, Q96EU7, Q9JMG2
• Gene Symbols: C1GALT1C1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG