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Invitrogen™ C19orf52 Polyclonal Antibody
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Product Code. 15727611 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15727611 100 μL 100µL
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Product Code. 15727611 Supplier Invitrogen™ Supplier No. PA559759

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LDVGFVGRWW VLGAWMRDCD INDDEFLHLP AHLRVVGPQQ LHSETNERLF DEKYKPVVLT DDQVDQALWE EQVLQKEKKD Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

TIMM29, also known as C19orf52, is identified as a novel subunit of the human TIM22 complex, which plays a critical role in the mitochondrial inner membrane. This protein is crucial for the stability of the TIM22 complex, which is responsible for the translocation of hydrophobic inner mitochondrial membrane proteins carrying internal targeting signals. TIMM29/C19orf52 is integrated into the mitochondrial inner membrane, exposing its C-terminus to the intermembrane space, and is vital for mitochondrial function and protein import pathways. This gene's importance is underscored by its involvement in processes related to mitochondrial integrity and its potential role in neurodegenerative disorders and viral interactions, such as those with the hepatitis B virus (HBV).
TRUSTED_SUSTAINABILITY

Specifications

Antigen C19orf52
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TIMM29
Gene Accession No. Q8BGX2, Q9BSF4
Gene Alias 1810026J23Rik; C19orf52; chromosome 19 open reading frame 52; Mitochondrial import inner membrane translocase subunit Tim29; RGD1309188; RIKEN cDNA 1810026J23 gene; similar to hypothetical protein BC011833; TIM29; TIMM29; uncharacterized protein C19orf52; uncharacterized protein C19orf52 homolog
Gene Symbols TIMM29
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human C19orf52. Recombinant protein control fragment (Product #RP-99123).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315463, 69773, 90580
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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