Invitrogen™ C15orf27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559788

Product Code. 15717641

Description

Immunogen sequence: SLSEDPCPSQ KALDPAPLAR PSPAGSAQTS PELEHRVSLF NQKNQEGFTV FQIRPVIHFQ PTVPMLEDKF RSLESKEQKL HRV Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.

Specifications

• Antigen: C15orf27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM266
• Gene Alias: 9630029F15; AI118078; C15orf27; expressed sequence AI118078; HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; HVRP1; Tmem266; Transmembrane protein 266; transmembrane protein C15orf27; transmembrane protein C15orf27 homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 123591
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2M3C6
• Gene Symbols: TMEM266
• Immunogen: Recombinant protein corresponding to Human C15orf27. Recombinant protein control fragment (Product #RP-98127).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG