Invitrogen™ C11orf30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596516

Product Code. 16579351

Description

Immunogen sequence: SLMEAQIDTN VEHMIVDPPK KALATSMLTG EAGSLPSTHM VVAGMANSTP QQQKCRESCS SPSTVGSSLT TRKIDPPAVP ATGQFMRIQN VGQKKAEESP AEIIIQAIPQ YAIPCHSSSN VVVEPSGLLE LNNFTSQQLD DEETAMEQDI DSSTEDGTEP SPSQSSAERS; Positive Samples: Mouse lung, Mouse brain, Mouse spleen, Mouse ovary, Mouse kidney; Cellular Location: Nucleus.

EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.

Specifications

• Antigen: C11orf30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EMSY
• Gene Alias: 2210018M11Rik; 2310016L09Rik; AU019521; AU019557; BRCA2-interacting transcriptional repressor EMSY; C11orf30; EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2 interacting transcriptional repressor; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; GL002; protein EMSY; RGD1310712; RIKEN cDNA 2210018M11 gene; similar to EMSY protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233545, 56946
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7Z589, Q8BMB0
• Gene Symbols: EMSY
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_0645782).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG