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c-Myc Mouse anti-Human, Clone: 9E10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6784-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15267947

  • £54.42 / 25µg


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For Research Use Only.


Specifications

Description

The 9E10 antibody reacts with human c-Myc p67; the antibody was raised against a synthetic peptide corresponding to amino acids 408-439 within the carboxy terminal domain of human c-Myc. This antibody can be used to detect myc-tagged protein. The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. C-Myc also plays a pivotal role in apoptosis, most notably its connections to the CD95/Fas death receptor pathway. These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes.
Description & Specifications

Specifications

c-Myc
9.00E+10
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
Myc proto-oncogene protein
IgG1
RUO
Primary
Human