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c-Myc Antibody (SPM237) - Azide and BSA Free, Novus Biologicals™

Product Code. 18334350 Shop All Bio Techne Products
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100 μg
Unit Size:
100µg
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18334350 100 μg 100µg
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Product Code. 18334350 Supplier Novus Biologicals Supplier No. NBP286682

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Description

Mouse Monoclonal Antibody

c-Myc Monoclonal specifically detects c-Myc in Human, Chicken (Negative), Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.
TRUSTED_SUSTAINABILITY

Specifications

Antigen c-Myc
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone SPM237
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation 10 mM PBS with No Preservative
Gene Alias avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)
Host Species Mouse
Immunogen A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-Myc, coupled to KLH. (Uniprot: P01106)
Purification Method Protein A or G purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Autophagy, Cancer, Cancer Stem Cells, Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, Epigenetics, Epitope Tags, Stem Cell Markers, Transcription Factors and Regulators, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 4609
Test Specificity It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This monoclonal antibody shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
Target Species Human, Chicken (Negative), Mouse (Negative), Rat (Negative)
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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