c-Met (HGF Receptor) Rat anti-Human, Clone: eBioclone 97, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8858-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238107

Quantity Price
1 £ 158.36 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
Applications Flow Cytometry
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene Alias hepatocyte growth factor receptor
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Antigen c-Met (HGF Receptor)
Regulatory Status RUO
Isotype IgG1
Quantity 100μg
Format Purified
Host Species Rat
Clone eBioclone 97
Conjugate Unlabeled
Species Reactivity Human

97 monoclonal antibody was generated against a human c-Met-Ig fusion protein, and reacts with human c-Met (HGFR)-transfected cells. Human c-Met is a 145kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma;. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.