C-1, Tocris Bioscience™

Description

Protein kinase inhibitor. Inhibits PKG, PKA and PKC (IC50 values are 4, 8 and 12 μM, respectively). Widely used as a ROCK inhibitor. Increases efficiency of human fibroblast reprogramming with PD 0325901 (Cat.No 4192), CHIR 99021 (Cat.No 4432), A 83-01 (Cat.No 2939) and hLIF. Improves survival of human pluripotent stem cells in culture.

Chemical Identifiers

• CAS: 84468-24-6
• Molecular Weight (g/mol): 277.34
• InChI Key: UPTYCYWTFGTCCG-UHFFFAOYSA-N
• PubChem CID: 3545
• SMILES: O=S(=O)(N1CCNCC1)C1=C2C=CN=CC2=CC=C1

• Molecular Formula: C13H15N3O2S
• MDL Number: MFCD00209852
• Synonym: 1-5-isoquinolinesulfonyl piperazine, ha 100 pharmaceutical, 1-5-isoquinolinylsulfonyl piperazine, chembl75773, 5-piperazine-1-sulfonyl isoquinoline, piperazine, 1-5-isoquinolinylsulfonyl, iqsp, 5-piperazin-1-ylsulfonyl isoquinoline, tocris-0543, c-i-qp
• IUPAC Name: 5-(piperazine-1-sulfonyl)isoquinoline

Specifications

• CAS: 84468-24-6
• MDL Number: MFCD00209852
• InChI Key: UPTYCYWTFGTCCG-UHFFFAOYSA-N
• IUPAC Name: 5-(piperazine-1-sulfonyl)isoquinoline
• PubChem CID: 3545
• Percent Purity: >99%

• Molecular Formula: C13H15N3O2S
• Synonym: 1-5-isoquinolinesulfonyl piperazine, ha 100 pharmaceutical, 1-5-isoquinolinylsulfonyl piperazine, chembl75773, 5-piperazine-1-sulfonyl isoquinoline, piperazine, 1-5-isoquinolinylsulfonyl, iqsp, 5-piperazin-1-ylsulfonyl isoquinoline, tocris-0543, c-i-qp
• SMILES: O=S(=O)(N1CCNCC1)C1=C2C=CN=CC2=CC=C1
• Molecular Weight (g/mol): 277.34
• Formula Weight: 277.34
• Chemical Name or Material: C-1

Safety and Handling

Recommended Storage : Store at Room Temperature