Butyryl chloride, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11374569	Thermo Scientific Alfa Aesar A17575.18	50 g
11418207	Thermo Scientific Alfa Aesar A17575.30	250 g
11408207	Thermo Scientific Alfa Aesar A17575.0B	1000 g

Description

Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

Solubility
Miscible with ether.

Notes
Moisture sensitive. Incompatible with water, alcohols, strong bases and strong oxidizing agents

Chemical Identifiers

• CAS: 141-75-3
• Molecular Weight (g/mol): 106.55
• InChI Key: DVECBJCOGJRVPX-UHFFFAOYSA-N
• PubChem CID: 8855
• SMILES: CCCC(Cl)=O

• Molecular Formula: C4H7ClO
• MDL Number: MFCD00000752
• Synonym: butyryl chloride, n-butyryl chloride, butyric acid chloride, butyroyl chloride, butyric chloride, butyrylchloride, unii-2xvm8e16ir, ccris 5989, n-butyric acid chloride, n-butanoyl chloride
• IUPAC Name: butanoyl chloride

Specifications

• CAS: 141-75-3
• Density: 1.026
• Flash Point: 18°C (64°F)
• Molecular Formula: C4H7ClO
• MDL Number: MFCD00000752
• Beilstein: 605395
• Merck Index: 14,1598
• Solubility Information: Miscible with ether.
• SMILES: CCCC(Cl)=O
• Molecular Weight (g/mol): 106.55
• Formula Weight: 106.55
• Chemical Name or Material: Butyryl chloride

• Melting Point: -89°C
• Boiling Point: 101°C to 102°C
• Odor: Acrid
• Refractive Index: 1.412
• UN Number: UN2353
• Sensitivity: Moisture sensitive
• Synonym: butyryl chloride, n-butyryl chloride, butyric acid chloride, butyroyl chloride, butyric chloride, butyrylchloride, unii-2xvm8e16ir, ccris 5989, n-butyric acid chloride, n-butanoyl chloride
• InChI Key: DVECBJCOGJRVPX-UHFFFAOYSA-N
• IUPAC Name: butanoyl chloride
• PubChem CID: 8855
• Percent Purity: 98%

Safety and Handling

GHS H Statement
H225-H314-H318
Highly flammable liquid and vapour.
Causes severe skin burns and eye damage.
Causes serious eye damage.

P210-P233-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H225-H302-H314-H331

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: BUTYRYL CHLORIDE

missing translation for 'einecsNumber' : 205-498-5

missing translation for 'rtecsNumber' : EM0595000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Substances and mixtures corrosive to metals Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H290-May be corrosive to metals.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H331-Toxic if inhaled.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

RUO – Research Use Only