Bumetanide, 98+%, Thermo Scientific™

Inhibitor of the sodium-potassium-chloride cotransporter

Brand:  Thermo Scientific Alfa Aesar J62302.03

Product Code. 15444709

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.

Chemical Identifiers

• CAS: 28395-03-1
• Molecular Weight (g/mol): 364.416
• InChI Key: MAEIEVLCKWDQJH-UHFFFAOYSA-N
• PubChem CID: 2471
• IUPAC Name: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid

• Molecular Formula: C17H20N2O5S
• MDL Number: MFCD00078949
• Synonym: bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
• ChEBI: CHEBI:3213
• SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Specifications

• CAS: 28395-03-1
• MDL Number: MFCD00078949
• Merck Index: 14,1484
• Solubility Information: Soluble in ethanol (10mg/ml),DMSO (25mg/ml),acetone,benzene,methanol,propylene glycol,and water (<1mg/ml).
• SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
• Molecular Weight (g/mol): 364.416
• ChEBI: CHEBI:3213
• Percent Purity: ≥98%

• Molecular Formula: C17H20N2O5S
• Quantity: 1g
• Synonym: bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
• InChI Key: MAEIEVLCKWDQJH-UHFFFAOYSA-N
• IUPAC Name: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
• PubChem CID: 2471
• Formula Weight: 364.4
• Chemical Name or Material: Bumetanide