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Invitrogen™ BRD7 Polyclonal Antibody
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Product Code. 16397174
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Quantity:
100 μL
Unit Size:
100µL
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16397174 100 μL 100µL
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Product Code. 16397174 Supplier Invitrogen™ Supplier No. PA578484

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Description

Rabbit Polyclonal Antibody

Positive Control: HeLa, HeLa nuclear extract Predicted Reactivity: Mouse (85%), Rat (84%), Bovine (88%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRD7
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene BRD7
Gene Accession No. Q9NPI1
Gene Alias 75 kDa bromodomain protein; BP75; BRD7; bromodomain containing 7; bromodomain protein 75 kDa; bromodomain-containing 7; bromodomain-containing 7-like protein; bromodomain-containing protein 7; CELTIX1; NAG4; protein CELTIX-1; protein tyrosine phosphatase, non-receptor type 13 interacting protein; Ptpn13ip
Gene Symbols BRD7
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human BRD7. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29117
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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