Invitrogen™ BRD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5109455

Product Code. 17187383

Description

Immunogen sequence: MLQNVTPHNK LPGEGNAGLL GLGPEAAAPG KRIRKPSLLY EGFESPTMAS VPALQLTPAN PPPPEVSNPK KPGRVTNQLQ YLHKVVMKAL WKHQFAWPFR.

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: BRD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BRD2
• Gene Alias: AW228947; Brd2; bromodomain containing 2; bromodomain-containing 2; bromodomain-containing protein 2; D17H6S113E; D6S113E; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Frg-1; FSH; Fsrg1; Fsrg-1; Kiaa4005; KIAA9001; mKIAA4005; Nat; O27.1.1; Protein RING3; Really interesting new gene 3 protein; RING3; RING3 protein; Rnf3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6046
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P25440
• Gene Symbols: BRD2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human BRD2 (NP_0050951).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG