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  5. Tocris Bioscience™ Bosentan

Tocris Bioscience™ Bosentan
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Product Code. p-7112428
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18758606

Brand: Tocris Bioscience™ 6232/10

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Description

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro. Orally bioavailable.
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Specifications

CAS 147536-97-8
Quantity 10 mg
Target Non-selective Endothelin Receptor
Molecular Formula C27H29N5O6S
Formula Weight 551.61g/mol
Product Type Antagonist

For Research Use Only

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