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Tocris Bioscience™ Bosentan

Product Code. 18758606
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Product Code. 18758606 Supplier Tocris Bioscience™ Supplier No. 6232/10

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79.90 GBP valid until 2026-03-31
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Description

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

CAS 147536-97-8
Quantity 10 mg
Target Non-selective Endothelin Receptor
Molecular Formula C27H29N5O6S
Formula Weight 551.61g/mol
Product Type Antagonist

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