Bortezomib, MedChemExpress

Product Code.	Quantity	unitSize
16476457	5 mg	5mg
16444796	100 mg	100mg
16413728	10 mg	10mg
16470107	50 mg	50mg
16470956	200 mg	200mg

Product Code. 16476457 Supplier Medchem Express Supplier No. HY10227

Description

MedChemExpress Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

Specifications

• Chemical Name or Material: Bortezomib
• CAS: 179324-69-7
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₁₉H₂₅BN₄O₄
• Quantity: 5 mg
• Synonym: PS-341 LDP-341 NSC 681239
• Solubility Information: Ethanol : 66.67 mg/mL (173.51 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
• SMILES: OB(O)[C@H](CC(C)C)NC([C@@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O
• Molecular Weight (g/mol): 384.24
• Formula Weight: 384.24
• Percent Purity: 98.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only