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Bortezomib, MedChemExpress

Product Code. 16444796
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Product Code. 16444796

Brand: Medchem Express HY10227

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Description

MedChemExpress Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

Specifications

Chemical Name or Material Bortezomib
CAS 179324-69-7
Color White
Purity Grade Notes Research
Molecular Formula C19H25BN4O4
Quantity 100 mg
Synonym PS-341 LDP-341 NSC 681239
Solubility Information Ethanol : 66.67 mg/mL (173.51 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
SMILES OB(O)[C@H](CC(C)C)NC([C@@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O
Molecular Weight (g/mol) 384.24
Formula Weight 384.24
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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