Invitrogen™ BNP Monoclonal Antibody (3A6F7C7)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA515363

Product Code. 11395333

Description

MA5-15363 targets BNP in indirect ELISA, IHC applications and shows reactivity with Human samples. The MA5-15363 immunogen is synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP, conjugated to KLH.

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Specifications

• Antigen: BNP
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P16860
• Gene Symbols: Nppb
• Immunogen: Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP, conjugated to KLH (aa 65-78).
• Regulatory Status: RUO
• Gene ID (Entrez): 4879
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: 3A6F7C7
• Conjugate: Unconjugated
• Gene: Nppb
• Gene Alias: 5 kDa cardiac natriuretic peptide; AA408272; Bnf; BNP; BNP(1-28); BNP(1-29); BNP(1-30); BNP(1-32); BNP(2-31); BNP(3-29); BNP(3-30); BNP(3-32); BNP(4-27); BNP(4-29); BNP(4-30); BNP(4-31); BNP(4-32); BNP(5-29); BNP(5-31); BNP(5-32); BNP-32; BNP-34; Brain natriuretic factor; brain natriuretic peptide; Brain natriuretic peptide 32; Brain natriuretic peptide 45; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide B; natriuretic peptide precursor B; natriuretic peptide precursor type B; natriuretic peptide type B; natriuretic peptides B; natriuretic protein; Nppb; type-B natriuretic factor
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1