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BNIP3L Polyclonal Antibody, Invitrogen™

Product Code. 11585992
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Quantity:
100 μg
Unit Size:
100µg
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11585992 100 μg 100µg
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Product Code. 11585992 Supplier Invitrogen Supplier No. PA112514

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Description

Rabbit Polyclonal Antibody

A suggested positive control for this product is K562 cell lysate.

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BNIP3L
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BNIP3L
Gene Accession No. O60238
Gene Alias BNIP3a, NIX
Gene Symbols BNIP3L
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 665
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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