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BNIP3L Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA112514
Code : LD
Additional Details : Weight : 0.01000kg
Description
A suggested positive control for this product is K562 cell lysate.
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.Specifications
BNIP3L | |
Polyclonal | |
PBS with 0.02% sodium azide | |
O60238 | |
BNIP3L | |
Synthetic peptide corresponding to residues 77-92 of human Bnip3L. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Western Blot | |
Unconjugated | |
BNIP3L | |
BNIP3a, NIX | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
665 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |