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BMS 193885, Tocris Bioscience™

Potent, competitive NPY Y1 receptor antagonist

£252.32 - £1015.92

Chemical Identifiers

CAS 679839-66-8
Molecular Formula C36H48N4O9
Molecular Weight (g/mol) 680.80
MDL Number MFCD16878998
InChI Key BYHJIPSVXAFCDI-UHFFFAOYNA-N
Synonym 1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
PubChem CID 56972234
IUPAC Name 2-hydroxypropanoic acid; 3,5-dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES CC(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(NC(=O)NCCCN2CCC(CC2)C2=CC(OC)=CC=C2)=CC=C1)C(=O)OC
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Product Code Brand Quantity Price Quantity & Availability  
18054652
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Tocris Bioscience
3242/10
10 mg
£252.32
10mg
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18085602
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Tocris Bioscience
3242/50
50 mg
£1015.92
50mg
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Description

Description

Potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. Reduces food intake and body weight via central Y1 inhibition and is brain penetrant.
Specifications

Chemical Identifiers

679839-66-8
680.80
BYHJIPSVXAFCDI-UHFFFAOYNA-N
56972234
CC(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(NC(=O)NCCCN2CCC(CC2)C2=CC(OC)=CC=C2)=CC=C1)C(=O)OC
C36H48N4O9
MFCD16878998
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
2-hydroxypropanoic acid; 3,5-dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Specifications

679839-66-8
MFCD16878998
BYHJIPSVXAFCDI-UHFFFAOYNA-N
2-hydroxypropanoic acid; 3,5-dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
56972234
>99%
C36H48N4O9
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
CC(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(NC(=O)NCCCN2CCC(CC2)C2=CC(OC)=CC=C2)=CC=C1)C(=O)OC
680.80
680.79
BMS 193885
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Recommended Storage : Desiccate at Room Temperature

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