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BMS 193885, Tocris Bioscience™

Catalog Number p-4783801
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
679839-66-8
C36H48N4O9
680.80
MFCD16878998
BYHJIPSVXAFCDI-UHFFFAOYNA-N
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
56972234
2-hydroxypropanoic acid; 3,5-dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CC(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(NC(=O)NCCCN2CCC(CC2)C2=CC(OC)=CC=C2)=CC=C1)C(=O)OC
This item is not returnable. View return policy
679839-66-8
C36H48N4O9
680.80
MFCD16878998
BYHJIPSVXAFCDI-UHFFFAOYNA-N
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
56972234
2-hydroxypropanoic acid; 3,5-dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CC(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1C1=CC(NC(=O)NCCCN2CCC(CC2)C2=CC(OC)=CC=C2)=CC=C1)C(=O)OC

Description

Potent, competitive NPY Y1 receptor antagonist

Potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. Reduces food intake and body weight via central Y1 inhibition and is brain penetrant.
Quantity 10 mg
Formula Weight 680.79
Percent Purity >99%
Chemical Name or Material BMS 193885
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