BMS-1166, MedChemExpress

Product Code.	Quantity	Unit Size
16484756	100 mg	100mg
16470067	50 mg	50mg
16432826	25 mg	25mg
16466417	5 mg	5mg
16473678	10 mg	10mg

Product Code. 16484756 Supplier Medchem Express Supplier No. HY102011

Descripción

MedChemExpress BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

Especificaciones

• Chemical Name or Material: BMS-1166
• CAS: 1818314-88-3
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₃₆H₃₃ClN₂O₇
• Quantity: 100 mg
• Solubility Information: DMSO : 125 mg/mL (194.97 mM; Need ultrasonic)
• SMILES: O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1
• Molecular Weight (g/mol): 641.11
• Formula Weight: 641.11
• Percent Purity: 98.37%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only