Invitrogen™ BMP-7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534602

Product Code. 15355521

Description

For Western Blot, this antibody has non-specific bands at 10 kDa,33 kDa and 38 kDa. Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with rabbit, horse, chicken and pig based on sequence homology.

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

Specifications

• Antigen: BMP-7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bmp7
• Gene Alias: BMP; BMP7; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; bone morphogenetic protein 7; bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 preproprotein; bone morphogenic protein 7; Eptotermin alfa; OP1; OP-1; Osteogenic protein 1; RP11-560A15.5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12162, 655, 85272
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P18075, P23359
• Gene Symbols: Bmp7
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 300 - 400 of Human BMP7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG