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Invitrogen™ BMI-1 Monoclonal Antibody (3E3)

Product Code. 12817942
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12817942 100 μL 100µL
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Product Code. 12817942 Supplier Invitrogen™ Supplier No. MA515919

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Description

Mouse Monoclonal Antibody

MA5-15919 targets BMI1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15919 immunogen is purified recombinant fragment of human BMI1 expressed in E. Coli. . MA5-15919 detects BMI1 which has a predicted molecular weight of approximately 37kDa.

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BMI-1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3E3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene BMI1
Gene Accession No. P25916, P35226
Gene Alias AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1
Gene Symbols BMI1
Host Species Mouse
Immunogen Purified recombinant fragment of human BMI1 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12151, 648
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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