Invitrogen™ Blood Group A Antigen Monoclonal Antibody (HE-193)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA544038

Product Code. 17624496

Description

This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1 and 2, A antigens with chain types 3, 4, 5, 6) and Forssman antigen.

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Specifications

• Antigen: Blood Group A Antigen
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 15mM sodium azide; pH 8
• Gene Accession No.: P16442
• Gene Symbols: ABO
• Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Agglutination, Immunohistochemistry (Paraffin), Immunohistochemistry (Paraffin)
• Clone: HE-193
• Conjugate: Unconjugated
• Gene: ABO
• Gene Alias: A transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; A3GALNT; A3GALT1; ABO; ABO A3 transferase; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; B transferase; B(A) alpha-1,3-galactosyltransferase; Blood Group A1; Blood Group A2; Blood Group A3; fucosylglycoprotein; fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; GTB; histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT; Transferase; transferase A
• Host Species: Mouse
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28
• Content And Storage: 4°C, do not freeze
• Form: Liquid