Invitrogen™ BLNK Monoclonal Antibody (5G9)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA515868

Product Code. 12817892

Description

MA5-15868 targets BLNK in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-15868 immunogen is purified recombinant fragment of human BLNK expressed in E. Coli. . MA5-15868 detects BLNK which has a predicted molecular weight of approximately 68kDa.

B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.

Specifications

• Antigen: BLNK
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: Q8WV28, Q9QUN3
• Gene Symbols: BLNK
• Immunogen: Purified recombinant fragment of human BLNK expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 17060, 29760
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5G9
• Conjugate: Unconjugated
• Gene: BLNK
• Gene Alias: AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1