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Invitrogen™ BLNK Monoclonal Antibody (5G9)

Product Code. 12817892
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12817892 100 μL 100µL
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Product Code. 12817892 Supplier Invitrogen™ Supplier No. MA515868

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Description

Mouse Monoclonal Antibody

MA5-15868 targets BLNK in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-15868 immunogen is purified recombinant fragment of human BLNK expressed in E. Coli. . MA5-15868 detects BLNK which has a predicted molecular weight of approximately 68kDa.

B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BLNK
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5G9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene BLNK
Gene Accession No. Q8WV28, Q9QUN3
Gene Alias AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Gene Symbols BLNK
Host Species Mouse
Immunogen Purified recombinant fragment of human BLNK expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17060, 29760
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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