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Invitrogen™ BICD1 Polyclonal Antibody

Product Code. 12848732
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Quantity:
100 μg
Unit Size:
100µg
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12848732 100 μg 100µg
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Product Code. 12848732 Supplier Invitrogen™ Supplier No. PA520555

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Daudi cell lysate. PA5-20555 can be used with blocking peptide PEP-0675.

BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BICD1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BICD1
Gene Accession No. Q8BR07, Q96G01
Gene Alias B830009D06Rik; bicaudal D homolog 1; bicaudal D homolog 1 (Drosophila); BICD; bic-D 1; BICD cargo adaptor 1; BICD1; cytoskeleton-like bicaudal D protein homolog 1; protein bicaudal D homolog 1
Gene Symbols BICD1
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human BICD1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12121, 362466, 636
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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