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BI-3802, MedChemExpress

Product Code. 16464228
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Product Code. 16464228

Brand: Medchem Express HY108705

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Description

MedChemExpress BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity.

BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity.

Specifications

Chemical Name or Material BI-3802
Physical Form Solid
CAS 2166387-65-9
Color White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C24H29ClN6O3
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 5 mg/mL (10.31 mM; Need ultrasonic)
SMILES ClC1=CN=C(N2C[C@H](C)C[C@H](C)C2)N=C1NC3=CC(C=C(OCC(NC)=O)C(N4C)=O)=C4C=C3
Molecular Weight (g/mol) 484.98
Formula Weight 484.98
Percent Purity 99.43%
Grade Research
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Research purposes only

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