Invitrogen™ BFSP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558401

Product Code. 15716281

Description

Immunogen sequence: LSRNYEEDVK LLHKQLAGCE LEQMDAPIGT GLDDILETIR IQWERDVEKN RVEAGALLQA KQQAEVAHMS QTQEEKLAAA LRVE Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%.

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Specifications

• Antigen: BFSP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BFSP2
• Gene Alias: 49 kDa cytoskeletal protein; AI448593; beaded filament protein CP49; beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; BFSP2; CP 47; CP47; CP49; CTRCT12; DKEYP-73D8.2; hypothetical protein LOC494090; lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; phakinin; PHAKOSIN; zgc:103750
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8419
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13515
• Gene Symbols: BFSP2
• Immunogen: Recombinant protein corresponding to Human BFSP2. Recombinant protein control fragment (Product #RP-96451).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG