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Invitrogen™ BFAR Polyclonal Antibody

Product Code. 12859032 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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12859032 100 μg 100µg
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Product Code. 12859032 Supplier Invitrogen™ Supplier No. PA520894

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human kidney tissue lysate. PA5-20894 can be used with blocking peptide PEP-1008.

The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BFAR
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BFAR
Gene Accession No. Q5PQN2, Q8R079, Q9NZS9
Gene Alias 3010001A07Rik; AI666707; AW107665; BAR; Bfar; bifunctional apoptosis inhibitor; bifunctional apoptosis regulator; RING finger protein 47; RNF47
Gene Symbols BFAR
Host Species Rabbit
Immunogen A 14 amino acid peptide near the carboxy terminus of human BFAR.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304709, 51283, 67118
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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