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BETd-260, MedChemExpress

Product Code. 16493398
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Product Code. 16493398 Supplier Medchem Express Supplier No. HY101519

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Description

MedChemExpress BETd-260 (ZBC 260) is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. BETd-260 potently suppresses cell viability and robustly induces apoptosis in hepatocellular carcinoma (HCC) cells.

BETd-260 (ZBC 260) is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4

Specifications

Chemical Name or Material BETd-260
CAS 2093388-62-4
Color Off-White
Purity Grade Notes Research
Molecular Formula C43H46N10O6
Quantity 10 mg
Synonym ZBC 260
Solubility Information DMSO : 25 mg/mL (31.29 mM; Need ultrasonic)
SMILES CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7
Molecular Weight (g/mol) 798.89
Formula Weight 798.89
Percent Purity 98.04%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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