Beta-Tubulin III Mouse, anti-Human, Unconjugated, Clone: 2G10-TB3, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60092.1

Product Code. 17138971

Description

• The 2G10-TB3 antibody reacts with beta-tubulin III, an ∼50 - 55 kDa structural protein that is a constituent of tubulin
• Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha- and beta-tubulin subunits
• The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types
• Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation
• It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells

Specifications

• Antigen: Beta-Tubulin III
• Classification: Monoclonal
• Conjugate: Unconjugated
• Quantity: 25 μg
• Target Species: Human, Rat, Mouse
• Cell Type: Neural Cells, PSC-Derived, Neurons

• Applications: Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: 2G10-TB3
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG2a κ