Invitrogen™ beta Lactamase Monoclonal Antibody (8A5.A10), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17810296	Invitrogen™ MA5-46004	100 μg
11578972	Invitrogen™ MA110712	500 μg
17840326	Invitrogen™ MA5-46119	1 mg

Description

MA1-10712 detects beta Lactamase from E. coli samples. MA1-10712 has been successfully used in ELISA and Western blot applications. The MA1-10712 immunogen is 5-His-tagged TEM-1 beta-lactamase.

The beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant.

Specifications

• Antigen: beta Lactamase
• Concentration: 1.6 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with no preservative; pH 7.4
• Immunogen: 5'-His-tagged TEM-1 beta-lactamase.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles

• Clone: 8A5.A10
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Bacteria
• Gene Alias: blaCTX-M-14; FLJ14902; G24; lactamase beta; LACTB; mitochondrial 39S ribosomal protein L56; MRPL56; Serine beta-lactamase-like protein LACTB, mitochondrial; UNQ843/PRO1781
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody