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Beta Catenin Rabbit anti-Human, CoraLite 594, Polyclonal, Proteintech

Product Code. 17234786 Shop All Proteintech Products
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Quantity:
100 μL
Unit Size:
100µL
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17234786 100 μL 100µL
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Product Code. 17234786 Supplier Proteintech Supplier No. CL59417565100UL

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Description

Rabbit Polyclonal Antibody

β-Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. β-Catenin was originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, β-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/β-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of β-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222)

Specifications

Antigen Beta Catenin
Applications Immunofluorescence
Classification Polyclonal
Concentration 1000 μg/mL
Conjugate CoraLite 594
Host Species Rabbit
Quantity 100 μL
Primary or Secondary Primary
Gene ID (Entrez) 1499
Target Species Human
Form Liquid
Isotype IgG
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