Invitrogen™ BERP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583900

Product Code. 16340855

Description

Immunogen sequence: QHKAALQRQL EAVRGRLPQL SAAIALVGGI SQQLQERKAE ALAQISAAFE DLEQALQQRK QALVSDLETI CGAKQKVLQ Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

The protein encoded by this gene is a member of the tripartite motif family, also called the 'RING-B-box-coiled-coil' subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Specifications

• Antigen: BERP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM3
• Gene Alias: Berp; BERP1; brain expressed ring finger; brain-expressed RING finger protein; Hac1; RING finger protein 22; RING finger protein 97; RING finger protein HAC1; RNF22; RNF97; Trim3; tripartite motif containing 3; tripartite motif protein 3; tripartite motif protein TRIM3; tripartite motif-containing 3; tripartite motif-containing protein 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10612
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75382
• Gene Symbols: TRIM3
• Immunogen: Recombinant protein corresponding to Human TRIM3. Recombinant protein control fragment (Product #RP-98384).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG