Alfa Aesar™ Benzenesulfonamide, 98+%


Overview
Brand: Alfa Aesar™

Manufacturer Part Number: A10891.30

BENZENESULFONAMIDE, 98+% 250G

UNSPSC: 12352111

Code: NEW

Additional Details:
Additional Details: CAS Number: 98-10-2 Weight: 0.01000kg


Quantity 250g

Product Code. 11494243

Quantity Price
1 £ 19.82 / 250g
Estimated Shipment date
from Supplier 31-01-2017
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Description and Specification

Chemical Identifiers

Chemical Name or Material Benzenesulfonamide
CAS 98-10-2
Molecular Formula C6H7NO2S
Formula Weight 157.19
MDL Number MFCD00007930
Beilstein 1100566

Specification

Formula Weight 157.19
Chemical Name or Material Benzenesulfonamide
TSCA TSCA
Assay ≥98%
Molecular Formula C6H7NO2S
MDL Number MFCD00007930
CAS 98-10-2
Beilstein 1100566
Health Hazard 1 Warning
Melting Point 151° to 154°C
Quantity 250g
Flash Point 250°C (482°F)
Odor Odorless
Health Hazard 2 GHS H Statement
H302
Harmful if swallowed.
Health Hazard 3 GHS P Statement
P280f
Wear protective clothing.
RTECS Number DA9380000

Applications
The presence of the benzenesulfonylamido (BS) groups shifted the activity of classic antimicrobial fluoroquinolones from being more active against Gram-negative to Gram-positive strains. Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. In engineering the specificity of antibacterial fluoroquinolones, benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.

Solubility
Soluble in methanol (25 mg/ml), and water (4.3 mg/ml at 16°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Safety and Handling

Warning

GHS H Statement
H302
Harmful if swallowed.

GHS P Statement
P280f
Wear protective clothing.