BD Recombinant Soluble Human Fas

Product Code. 15867648

Brand: BD 554336

Description

Expressed in the Baculovirus expression vector system and purified from insect cell lysate using an anti-Fas antibody, this protein lacks the transmembrane domain of the Fas receptor

Fas (APO-1, CD95) is an ∽42 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissue and cells including the thymus, liver, ovary and lung. FasL is a 40 kDa TNF family member membrane protein that induces apoptosis by binding to Fas, its cell-surface receptor. FasL is expressed on activated T and NK cells. Both Fas and FasL are thought to play an important role in the apoptotic processes that take place during T cell development. FasδTM has 63-base pair deletion starting at nucleotide sequence (700) GA TCC AGA and ending at nucleotide sequence GTT TGG G (762).FasδTM has a reduced molecular weight of ∽40 kDa.

• Alias: FasδTM
• Molecular weight: ∽40 kDa
• Storage buffer: Aqueous buffered solution containing BSA and glycerol
• Protein purity and integrity were verified by SDS-PAGE, and ELISA

Avoid multiple freeze-thaws of product.

Western blot, ELISA Standard, Functional assay

Specifications

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: Aqueous Buffered solution containing BSA and Glycerol
• Molecular Weight (g/mol): 42
• Name: Fas (Soluble) Recombinant Human Protein
• Preparation Method: Expressed in the Baculovirus expression vector system and purified from insect cell lysate using an anti-Fas Antibody
• Purification Method: ELISA, SDS-PAGE
• Quantity: 10 μg
• Storage Requirements: -80°C
• Recombinant: Recombinant
• Form: Solution

Research use only.