BD Ac-IETD-CHO Caspase-8 Inhibitor

To study caspase-8 activity in apoptotic cell lysates

Brand:  BD 556554

Product Code. 15888728

Description

Members of caspase family have key roles in inflammation and mammalian apoptosis. Caspase-8 (FLICE/MACH-1) is a 55 kDa cytosolicprotein with homology to the CD95/Fas-associated signal transduction molecule, FADD, in addition to its homology with other caspases. Caspase-8 is activated early in apoptosis and is involved in the proteolysis and activation of pro-caspase-3

• Synthetic tetrapeptide inhibitor of caspase-8
• Contains the amino acid sequence that is the target for caspase-8 mediated proteolysis
• Used as a negative (blocking) control
• May be used in protease assays
• Format: Purified

Fluorescence quantitation

Specifications

• For Use With (Application): Fluorescence quantitation
• Content And Storage: -20°C
• Molecular Weight (g/mol): 55
• Form: Purified

• Storage Buffer: Lyophilized in Dimethyl Sulfoxide
• Quantity: 1 mg
• Inhibitors: Ac-IETD-CHO

Research use only