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Invitrogen™ BCLAF1 Polyclonal Antibody
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Product Code. 15793601
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Quantity:
100 μL
Unit Size:
100µL
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15793601 100 μL 100µL
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Product Code. 15793601 Supplier Invitrogen™ Supplier No. PA555686

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QKSPEIHRRI DISPSTLRKH TRLAGEERVF KEENQKGDKK LRCDSADLRH DIDRRRKERS KERGDSKGSR ESSGSRKQEK TPKDYKEYKS YKDDSKHKRE QDHSRSSSSS ASPSSPSSR Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCLAF1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BCLAF1
Gene Accession No. Q9NYF8
Gene Alias 2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Gene Symbols BCLAF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BCLAF1. Recombinant protein control fragment (Product #RP-89287).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9774
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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