Invitrogen™ BCL7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582696

Product Code. 16369654

Description

Immunogen sequence: QADGKEHPGA EDASDEQNSQ SSMEHSMNSS EKVDRQPSGD SGLAAETSAI SQDLEGVPPS KKMKLEASQQ NSE Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 89%.

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: BCL7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCL7A
• Gene Alias: 4432415N06Rik; AI448316; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL 7; BCL tumor suppressor 7A; BCL7; Bcl7a; LOC690085; similar to B-cell CLL/lymphoma 7A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 605
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q4VC05
• Gene Symbols: BCL7A
• Immunogen: Recombinant protein corresponding to Human BCL7A. Recombinant protein control fragment (Product #RP-92559).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG