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Invitrogen™ BCL2L10 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100704

Artikelnummer. 16677184

  • £448.00 / 100µL

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Beskrivelse

Beskrivelse

Antibody detects endogenous levels of total BCL2L10.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

BCL2L10
Polyclonal
Unconjugated
BCL2L10
AA420380; anti-apoptotic protein Boo; Anti-apoptotic protein NrH; apoptosis regulator Bcl-B; AU023065; Bcl-2 homolog Diva; BCL2 like 10; BCL2L10; bcl2-L-10; Bcl2-like 10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCLB; BCL-B; Boo; C85687; death inducer binding to vBcl-2 and Apaf-1; Diva
Rabbit
Affinity chromatography
RUO
10017, 12049
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9HD36, Q9Z0F3
BCL2L10
A synthesized peptide derived from human BCL2L10(Accession Q9HD36), corresponding to amino acid residues G122-Q172.
100 μL
Primary
Human, Mouse
Antibody
IgG
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