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Invitrogen™ BCL2A1 Polyclonal Antibody

Product Code. 12828462
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Quantity:
100 μg
Unit Size:
100µg
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12828462 100 μg 100µg
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Product Code. 12828462 Supplier Invitrogen™ Supplier No. PA520268

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Description

Rabbit Polyclonal Antibody

Despite the predicted molecular weight, Bfl-1 often migrates at a higher molecular weight in SDS-PAGE, presumably due to post-translational modifications. A suggested positive control is human kidney tissue lysate. PA5-20268 can be used with blocking peptide PEP-0383.

Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL2A1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene BCL2A1
Gene Accession No. Q07440, Q16548
Gene Alias A1; A1-A; ACC1; ACC-1; ACC2; ACC-2; B cell leukemia/lymphoma 2 related protein A1a; BB218357; B-cell leukemia/lymphoma 2 related protein A1; B-cell leukemia/lymphoma 2 related protein A1a; B-cell leukemia/lymphoma 2 related protein A1d; BCL2 related protein A1; Bcl2a1; Bcl2a1a; Bcl2a1d; BCL2L5; bcl2-L-5; Bcl-2-like protein 5; bcl-2-related protein A1; BCL2-related protein A1; BCL2-related protein A1d; Bfl1; Bfl-1; GRS; GRS protein; HBPA1; hematopoietic BCL2-related protein A1; hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Gene Symbols BCL2A1, Bcl2a1a
Host Species Rabbit
Immunogen A 14 amino acid peptide from near the carboxy terminus of human Bfl-1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12044, 597
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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