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Invitrogen™ BCL-XL Recombinant Rabbit Monoclonal Antibody (HL2038)

Product Code. 30274840
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Quantity:
100 μL
Unit Size:
100µL
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30274840 100 μL 100µL
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Product Code. 30274840 Supplier Invitrogen™ Supplier No. MA556609

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Description

Rabbit Recombinant Monoclonal Antibody

BCL-XL Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL-XL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2038
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene BCL2L1
Gene Accession No. P53563, Q07817, Q64373
Gene Alias anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
Gene Symbols BCL2L1
Host Species Rabbit
Immunogen Recombinant fragment of human Bcl-XL.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12048, 24888, 403618, 493701, 598
Target Species Human, Mouse, Rat, Canine, Feline
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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