Invitrogen™ Bcl-W Monoclonal Antibody (90316)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561930

Product Code. 30535836

Description

Bcl-W Monoclonal Antibody for Western Blot

Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The 'rox' portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.

Specifications

• Antigen: Bcl-W
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q92843
• Gene Symbols: BCL2L2
• Immunogen: E. coli-derived recombinant human Bcl-w, Met1-Thr172.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 90316
• Conjugate: Unconjugated
• Gene: BCL2L2
• Gene Alias: Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 599
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized