Invitrogen™ BCL-10 Recombinant Rabbit Monoclonal Antibody (23GB1210), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA553201

Product Code. 30087494

Description

BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.

Specifications

• Antigen: BCL-10
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: BCL10
• Gene Alias: AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8915
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB1210
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O95999
• Gene Symbols: BCL10
• Immunogen: A synthesized peptide derived from human Bcl10 (1-233AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG