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BAY-677, MedChemExpress

Product Code. 16484458
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Product Code. 16484458

Brand: Medchem Express HY111457

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Description

MedChemExpress BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

Specifications

Chemical Name or Material BAY-677
Physical Form Solid
CAS 2117404-84-7
Color Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C20H15F3N4O2
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : ≥ 50 mg/mL (124.89 mM)
SMILES N#CC1=NC=C([C@@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1
Molecular Weight (g/mol) 400.35
Formula Weight 400.35
Percent Purity 98.02%
Grade Research
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Research purposes only

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